Diazepam is N-demethylated by CYP3A4 and 2C19 to the Lively metabolite N-desmethyldiazepam, and it is hydroxylated by CYP3A4 to the active metabolite temazepam. N-desmethyldiazepam and temazepam are both of those even further metabolized to oxazepam. Temazepam and oxazepam are largely eradicated by glucuronidation.Simply call your Health care suppl